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Medicinal Chemistry III Book B.Pharm 6th Semester

Click below to Buy E-Book Edition:
We are providing Medicinal Chemistry-3 Book for B.Pharm 6th Semester students by Thakur Publication. Medicinal Chemistry-III Book is very helpful for b.pharm students.
The Medicinal Chemistry-3 book is an essential guide for B.Pharm 6th semester students looking to expand their knowledge of drug design and development. This comprehensive guide covers essential topics such as heterocyclic chemistry, drug metabolism, and prodrugs.
UPDATED EDITION · EXAM-READY MATERIAL · FAST DELIVERY
With practical examples and case studies, this book is a must-have for anyone interested in medicinal chemistry. Order your copy today!
Dr. (Prof.) V.N. Indulatha, Dr. Rakesh Kumar, Dr. Neha Tiwari
ISBN No.: 978-93-89627-60-2
₹230.00
Tax excluded
Click below to Buy E-Book Edition:
We are providing Medicinal Chemistry-3 Book for B.Pharm 6th Semester students by Thakur Publication. Medicinal Chemistry-III Book is very helpful for b.pharm students.
The Medicinal Chemistry-3 book is an essential guide for B.Pharm 6th semester students looking to expand their knowledge of drug design and development. This comprehensive guide covers essential topics such as heterocyclic chemistry, drug metabolism, and prodrugs.
UPDATED EDITION · EXAM-READY MATERIAL · FAST DELIVERY
With practical examples and case studies, this book is a must-have for anyone interested in medicinal chemistry. Order your copy today!
Dr. (Prof.) V.N. Indulatha, Dr. Rakesh Kumar, Dr. Neha Tiwari
ISBN No.: 978-93-89627-60-2
Syllabus
Module 01 10 Hours
Antibiotics
Historical background, Nomenclature, Stereochemistry, Structure activity relationship, Chemical degradation classification and important products of the following classes.
β-Lactam antibiotics
- Penicillin, Cepholosporins, β- Lactamase inhibitors, Monobactams.
Aminoglycosides
- Streptomycin, Neomycin, Kanamycin.
Tetracyclines
- Tetracycline, Oxytetracycline, Chlortetracycline, Minocycline, Doxycycline.
Module 02 10 Hours
Antibiotics
Historical background, Nomenclature, Stereochemistry, Structure activity relationship, Chemical degradation classification and important products of the following classes.
Macrolide
- Erythromycin Clarithromycin, Azithromycin.
Miscellaneous
- Chloramphenicol*, Clindamycin.
Pro-drugs
- Basic concepts and application of prodrugs design.
Antimalarials
- Etiology of malaria.
Quinolines
- SAR, Quinine sulphate, Chloroquine, Amodiaquine, Primaquine phosphate, Pamaquine, Quinacrine hydrochloride, Mefloquine.
- Biguanides and dihydro triazines
- Cycloguanil pamoate, Proguanil.
Miscellaneous
- Pyrimethamine, Artesunete, Artemether, Atovoquone.
Module 03 10 Hours
Anti-Tubercular Agents
Synthetic Anti-Tubercular Agents
- Isoniozid, Ethionamide, Ethambutol, Pyrazinamide, Para amino salicylic acid.
Anti-Tubercular Antibiotics
- Rifampicin, Rifabutin, Cycloserine Streptomycine, Capreomycin sulphate.
Urinary Tract Anti-Infective Agents
Quinolones
- SAR of quinolones, Nalidixic Acid, Norfloxacin, Enoxacin, Ciprofloxacin, Ofloxacin, Lomefloxacin, Sparfloxacin, Gatifloxacin, Moxifloxacin.
Miscellaneous
- Furazolidine, Nitrofurantoin*, Methanamine.
Antiviral Agents
- Amantadine hydrochloride, Rimantadine hydrochloride, Idoxuridine trifluoride, Acyclovir*, Gancyclovir, Zidovudine, Didanosine, Zalcitabine, Lamivudine, Loviride, Delavirding, Ribavirin, Saquinavir, Indinavir, Ritonavir.
Module 04 08 Hours
Antifungal Agents
Antifungal Antibiotics
- Amphotericin-B, Nystatin, Natamycin, Griseofulvin.
Synthetic Antifungal Agents
- Clotrimazole, Econazole, Butoconazole, Oxiconazole Tioconozole, Miconazole, Ketoconazole, Terconazole, Itraconazole, Fluconazole, Naftifine hydrochloride, Tolnaftate.
Anti-Protozoal Agents
- Metronidazole, Tinidazole, Ornidazole, Diloxanide, Iodoquinol, Pentamidine Isethionate, Atovaquone, Eflornithine.
Anthelmintics
- Diethylcarbamazine citrate, Thiabendazole, Mebendazole, Albendazole, Niclosamide, Oxamniquine, Praziquantal, Ivermectin.
Sulphonamides and Sulfones
- Historical development, chemistry, classification and SAR of Sulfonamides: Sulphamethizole, Sulfisoxazole, Sulphamethizine, Sulfacetamide, Sulphapyridine, Sulfamethoxaole, Sulphadiazine, Mefenide acetate, Sulfasalazine.
Folate Reductase Inhibitors
- Trimethoprim*, Cotrimoxazole.
Sulfones
- Dapsone.
Module 05 07 Hours
Introduction to Drug Design
- Various approaches used in drug design.
- Physicochemical parameters used in quantitative structure activity relationship (QSAR) such as partition coefficient, Hammet’s electronic parameter, Tafts steric parameter and Hansch analysis.
- Pharmacophore modeling and docking techniques.
Combinatorial Chemistry
- Concept and applications of combinatorial chemistry: solid phase and solution phase synthesis.
PCI2021/B.Pharm/6/01
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