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Zoology (Gene Technology, Immunology and Computational Biology) Book B.Sc 4th Sem

Click below to Buy E-Book Edition:
AUTHORS : Dr. Lalit Gupta, Dr. Kumud Rai
ISBN : 9789357550338
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Click below to Buy E-Book Edition:
AUTHORS : Dr. Lalit Gupta, Dr. Kumud Rai
ISBN : 9789357550338
Syllabus of UP State Universities and Colleges
Course Code: B050401T
Gene Technology, Immunology and Computational Biology
Unit
|
Topic |
Total No. of Lectures (60) |
I |
Principles of Gene Manipulation · Recombinant DNA Technology · Selection and identification of recombinant cells · Restriction enzymes, DNA modifying enzymes, Cloning Vectors, Ligation · Gene transfer techniques, Gene therapy |
10 |
II |
Applications of Genetic Engineering · Single cell proteins · Biosensors, Biochips · Crop and live stock improvement, Development of transgenics · Development of DNA drugs and vaccines |
8 |
III |
DNA Diagnostics · Genetic analysis of human diseases, Detection of known and unknown mutations · Concept of pharmacogenomics and pharmacogenetics |
4 |
IV |
Immune System and its Components · Historical perspective of Immunology, Innate and Adaptive Immunity, Clonal selection, Complement system · Structure and functions of different classes of immunoglobulins, Hypersensitivity · Humoral immunity and cell mediated immunity · HLA complex: Organisation, class I and II HLA molecules |
10 |
V |
Biostatistics I · Calculations of mean, median, mode, variance, standard deviation · Concepts of coefficient of variation, Skewness, Kurtosis · Elementary idea of probability and application |
7 |
VI |
Biostatistics II · Data summarizing: Frequency distribution, Graphical presentation—Bar, Pie diagram, Histogram · Tests of significance: One and two sample tests, t-test and Chisquare test |
7 |
VII |
Basics of Computers · Basics (CPU, I/O units) and Operating systems · Concept of homepages and websites, World Wide Web, URLs, using search engines |
6 |
VIII |
Bioinformatics · Databases: Nucleic acids, Genomes, Protein sequences and structures, Bibliography · Sequence analysis (homology): Pairwise and multiple sequence alignments-Blast, Clustalw · Phylogenetic analysis |
8 |