Controlled Drug Delivery Systems
- Introduction, terminology/definitions and rationale, advantages, disadvantages,
selection of drug candidates.
- Approaches to design controlled release formulations based on diffusion,
dissolution and ion exchange principles.
- Physicochemical and biological properties of drugs relevant to controlled release
- Introduction, classification, properties, advantages and application of polymers in
formulation of controlled release drug delivery systems.
- Definition, advantages and disadvantages, microspheres /microcapsules,
microparticles, methods of microencapsulation, applications.
Mucosal Drug Delivery system
- Introduction, Principles of bioadhesion/ mucoadhesion, concepts, advantages
anddisadvantages, transmucosal permeability and formulation considerations of buccal delivery systems
Implantable Drug Delivery System
- Introduction, advantages and disadvantages, concept of implants and osmotic pump.
Transdermal Drug Delivery Systems
- Introduction, Permeation through skin, factors affecting permeation, permeation
enhancers, basic components of TDDS, formulation approaches
Gastroretentive Drug Delivery Systems
- Introduction, advantages, disadvantages, approaches for GRDDS – Floating,
highdensity systems, inflatable and gastro-adhesive systems and their applications
Nasopulmonary Drug Delivery System
- Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of
Inhalers (dry powder and metered dose), nasal sprays, nebulizers.
Targeted Drug Delivery
- Concepts and approaches advantages and disadvantages, introduction to liposomes,
niosomes, nanoparticles, monoclonal antibodies and their applications.
Ocular Drug Delivery Systems
- Introduction, intra ocular barriers and methods to overcome –Preliminary study,
Ocular formulations and ocuserts.
Intrauterine Drug Delivery Systems
- Introduction, advantages and disadvantages, development of intra uterine devices
(IUDs) and applications.