Pharmacology-I

Unit

Content

Time

(Hrs)

I

Introduction to Pharmacology

·        Definitions & Branches

·        Nature & Sources of drugs

·        Dosage Forms and Routes of drug administration

·        Terminology used

·        Classification, Abbreviations, Prescription, Drug Calculation, Weights and Measures

·        Pharmacodynamics: Actions, Drug Antagonism, Synergism, Tolerance, Receptors, Therapeutic, adverse, toxic effects, pharmacovigilance

·        Pharmacokinetics: Absorption, Bioavailability, Distribution, Metabolism, Interaction, Excretion

·        Review: Principles of drug administration and treatment individualization

• Factors affecting dose, route etc.

·        Indian Pharmacopoeia: Legal Issues, Drug Laws, Schedule Drugs

·        Rational Use of Drugs

·        Principles of Therapeutics

3

II

Pharmacology of Commonly Used Antiseptics and Disinfectants

·        Antiseptics and Disinfectants

·        Composition, action, dosage, route, indications, contraindications, Drug interactions, side effects, adverse effects, toxicity and role of nurse

1

III

Drugs Acting on G.I. System

·        Pharmacology of commonly used drugs

• Emetics and Antiemetics

• Laxatives and Purgatives

• Antacids and antipeptic ulcer drugs

• Anti-diarrhoeals – Fluid and electrolyte therapy, Furazolidone, dicyclomine

·        Composition, action, dosage, route, indications, contraindications, drug interactions, side effects, adverse effects, toxicity and role of nurse

2

IV

Drugs Acting on Respiratory System

·        Pharmacology of commonly used

• Antiasthmatics – Bronchodilators (Salbutamol inhalers)

• Decongestants

• Expectorants, Antitussives and Mucolytics

• Broncho-constrictors and Antihistamines

·        Composition, action, dosage, route, indications, contraindications, drug interactions, side effects, adverse effects toxicity and role of nurse

2

V

Drugs Used in Treatment of Cardiovascular System and Blood Disorders

·        Haematinics, & treatment of anemia and antiadrenergics

·        Cholinergic and anticholinergic

·        Adrenergic Drugs for CHF & vasodilators

·        Antianginals

·        Antiarrhythmics

·        Antihypertensives

·        Coagulants & Anticoagulants

·        Antiplatelets & thrombolytics

·        Hypolipidemics

·        Plasma expanders & treatment of shock

·        Drugs used to treat blood disorders

·        Composition, action, dosage, route, indications, contraindications, drug interactions, side effects, adverse effects, toxicity and role of nurse

4

VI

Drugs Used in Treatment of Endocrine System Disorders

·        Insulin & oral hypoglycemics

·        Thyroid and anti-thyroid drugs

·        Steroids

• Corticosteroids

• Anabolic steroids

·        Calcitonin, parathormone, vitamin D3, calcium metabolism

• Calcium salts

2

VII

Drugs Used in Treatment of Integumentary System

·        Antihistaminics and antipruritics

·        Topical applications for skin- Benzylbenzoate, Gamma BHC, Clotrimazole, Miconazole, Silver Sulphadiazine (burns)

·        Composition, action, dosage, route, indications, contraindications, drug interactions, side effects, adverse effects toxicity and role of nurse

1

VIII

Drugs Used in Treatment of Communicable Diseases (common infections, infestations)

·        General Principles for use of Antimicrobials

·        Pharmacology of commonly used drugs:

• Penicillin, Cephalosporin‘s, Aminoglycosides, Macrolide & broad spectrum antibiotics, Sulfonamides, quinolones, Misc. antimicrobials

·        Anaerobic infections

·        Antitubercular drugs,

·        Antileprosy drugs

·        Antimalarials

·        Antiretroviral drugs

·        Antiviral agents

·        Antihelminthics, Antiscabies agents

·        Antifungal agents

·        Composition, action, dosage, route, indications, contraindications, Drug interactions, side effects, adverse effects, toxicity and role of nurse

5